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I use two mIRc scripts to chat, probably the best ones i know, so a new standard mIRC 6.21 has been released, DOWNLOAD IT HERE
Get latest updated server list HERE which you put in mIRC directory.

IRC (Internet Relay Chat) is a virtual meeting place where people from all over the world can meet and talk; you’ll find the whole diversity of human interests, ideas, and issues here, and you’ll be able to participate in group discussions on one of the many thousands of IRC channels, on hundreds of IRC networks, or just talk in private to family or friends, wherever they are in the world.
mIRC is a highly configurable IRC client with all the goodies other clients on UNIX, Macintosh and even Windows, combined with a nice and clean user interface. mIRC offers full color text lines, DCC File Send and Get capabilities, programmable aliases, a remote commands and events handler, place sensitive popup menu’s, Switchbar, World Wide Web and sound support, and more.

Most downloaded script i know is www.NNscript.de
Download Nnscript HERE

Here are a few examples of some of the features included in the script:

* Away system with pager and log
* Balloon tips to notify you of events
* Customizable toolbar with e-mail checker, lag graph and much more
* Control centers for psyBNC and QuakeNet’s Q and L bots
* Extensive channel and personal protections
* Game support for launching games by clicking on an IP address or selecting favorite servers
* Improved channel central with topic preview, extended modes and ban control
* RSS newsticker support
* Statistics, system information and usage histories
* Theme engine with lots of themes and easy editing
* Treeview switchbar for easily keeping track of your channels and queries
* A clipboard editor, blacklist, clone scanner, alarm timer, kick/ban/dcc histories and much, much more…

And Good and simple script to download is NBS-irc which can show what music you play from Winamp, Script is small fast with a lot of features to play.
Download NBS irc HERE